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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EPS8L2 All Species: 7.27
Human Site: S404 Identified Species: 22.86
UniProt: Q9H6S3 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H6S3 NP_073609.2 715 80621 S404 E S W M R P R S E W P R E P Q
Chimpanzee Pan troglodytes XP_512904 745 82543 L441 D S W T R P G L E L P P E E G
Rhesus Macaque Macaca mulatta XP_001116697 615 68955 P339 L T L R A R P P S E G E F V D
Dog Lupus familis XP_534881 791 88639 A388 E T W M K A R A E W P K E Q F
Cat Felis silvestris
Mouse Mus musculus Q99K30 729 82211 S407 E T W M R P R S E W P R E P Q
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510664 556 62861 F280 F Q K V K C S F N L L G M L S
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002666818 677 76506 A392 D G W T R P R A D W P K D Q C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785396 970 107261 T558 R A W T L P S T E W P K D R P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 42.2 79.7 42.5 N.A. 84 N.A. N.A. 29 N.A. N.A. 56.5 N.A. N.A. N.A. N.A. 24.6
Protein Similarity: 100 58.2 80.8 60.1 N.A. 90.1 N.A. N.A. 46.1 N.A. N.A. 70.7 N.A. N.A. N.A. N.A. 40.5
P-Site Identity: 100 46.6 0 53.3 N.A. 93.3 N.A. N.A. 0 N.A. N.A. 40 N.A. N.A. N.A. N.A. 33.3
P-Site Similarity: 100 53.3 6.6 80 N.A. 100 N.A. N.A. 13.3 N.A. N.A. 73.3 N.A. N.A. N.A. N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 0 0 13 13 0 25 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 13 % C
% Asp: 25 0 0 0 0 0 0 0 13 0 0 0 25 0 13 % D
% Glu: 38 0 0 0 0 0 0 0 63 13 0 13 50 13 0 % E
% Phe: 13 0 0 0 0 0 0 13 0 0 0 0 13 0 13 % F
% Gly: 0 13 0 0 0 0 13 0 0 0 13 13 0 0 13 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 13 0 25 0 0 0 0 0 0 38 0 0 0 % K
% Leu: 13 0 13 0 13 0 0 13 0 25 13 0 0 13 0 % L
% Met: 0 0 0 38 0 0 0 0 0 0 0 0 13 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 63 13 13 0 0 75 13 0 25 13 % P
% Gln: 0 13 0 0 0 0 0 0 0 0 0 0 0 25 25 % Q
% Arg: 13 0 0 13 50 13 50 0 0 0 0 25 0 13 0 % R
% Ser: 0 25 0 0 0 0 25 25 13 0 0 0 0 0 13 % S
% Thr: 0 38 0 38 0 0 0 13 0 0 0 0 0 0 0 % T
% Val: 0 0 0 13 0 0 0 0 0 0 0 0 0 13 0 % V
% Trp: 0 0 75 0 0 0 0 0 0 63 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _